How and Why Prilosec OTC Works

Prilosec OTC is formulated to block heartburn before it begins.

It works by stopping heartburn at its source: acid production. During the digestive process, the stomach produces acid to break down food. Normally, your lower esophageal sphincter, or LES, opens and closes to let food pass from your esophagus into your stomach. When your LES relaxes, excess acids flow up, or reflux, into your esophagus creating the painful sensation of heartburn.

The acid is produced by millions of tiny pumps in your stomach lining. Prilosec OTC works by directly blocking many of these active stomach pumps that produce acid.

With fewer active pumps, your stomach produces enough acid to break down food but not the excess acid that causes the pain of heartburn.

With Prilosec OTC, you can block the pain of frequent heartburn for 24 hours with one pill a day*.