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Prilosec OTC: The #1 Doctor Recommended Medicine for Frequent Heartburn

About 20 percent of Americans experience frequent heartburn. When that burning sensation hits, many will reach for the over-the-counter remedy that relieves their frequent heartburn fast. But does it provide relief for 24-hours with only 1 pill a day?* There are many different types of over-the-counter heartburn products available, however they don’t all offer the same relief as a PPI, like Prilosec OTC.

PPIs provide the longest lasting relief from frequent heartburn with 1 pill a day

The majority of heartburn medications are antacids, acid controllers, and proton pump inhibitors (PPIs).

Antacids: Antacids simply neutralize stomach acid. While they are fast-acting, they only provide 1-3 hours of relief. If you’re experiencing heartburn frequently, just imagine having to carry antacids with you everywhere you go just to be prepared.

Acid controllers: Acid controllers, or H2 blockers, partially reduce stomach acid production by blocking Histamine 2 receptors, which stimulate stomach acid production. H2 blockers can work in as little as 30 minutes and can provide 8-12 hours of relief. If you take one in the morning, it can get you through your day…but what happens when you start to feel the heartburn around dinner time?

Proton Pump Inhibitors (PPIs): Proton pump inhibitors, like Prilosec OTC, block acid production at the source. They generally take 1-4 days to fully kick in but relief lasts a full 24-hours. The best part? You only need to take 1 pill a day! PPIs are recommended most often by doctors to treat frequent heartburn.

Prilosec OTC is Proven & Trusted by Doctors...


Doctors have recommended Prilosec OTC for more than 14 years to help millions of people suffering from frequent heartburn.^ It has been tried by more than 30 million Americans and is one of the most effective heartburn brands.** If you suffer from frequent heartburn, talk to your doctor about trying Prilosec OTC.

…And by people suffering from frequent heartburn

If you think Prilosec OTC could be right for you, sign-up for the Two Week Challenge and get $3 off to help you get started. Try 1 pill a day for 14 days to experience what zero heartburn feels like.*

**PG Calculation based in part on Buying Households reported by the Nielsen Company through its Homescan Panel service in the US for Prilosec OTC for the period of 8/31/03 through 6/25/16

Sources (Accessed June 2020)