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Why should I take Prilosec OTC?

You can't beat zero heartburn!*. Prilosec OTC helps you find long-lasting relief from frequent heartburn when you need it most. Here are just a few reasons why you should consider Prilosec OTC:

1 All day and all night heartburn protection
Prilosec OTC starts working on Day 1 to block heartburn for 24 hours so you can live life heartburn-free

2 Blocks Heartburn before it starts
Prilosec OTC works by preventing excess acid production, tackling the root cause of your heartburn instead of just masking the symptoms

3 Simple, Effective Heartburn Relief
Just 1 pill each morning is all it takes for relief that lasts all day and night! No more juggling multiple doses or treatments

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Start your journey to ZERO HEARTBURN*with Prilosec OTC

Choose between the classic Unflavored Prilosec OTC or Prilosec OTC WildBerry for a tasty burst of flavor.

Relief you can trust withPRILOSEC OTC

Helpful Resources

^ IQVIA ProVoice Survey, 2005-2025.

†Pharmacy Times 2025-2026 Survey of Pharmacists’ OTC Recommendations

* Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Use as directed.

** PG Calculation based in part on Buying Households reported by the Nielsen Company through its Homescan Panel service in the US for Prilosec OTC for the period of 8/31/03 through 6/25/16