Prilosec OTC FAQs: How it Works and How to Take It

How one pill a day can treat your frequent hearburn.*

Prilosec OTC can stop frequent heartburn before it begins. With one pill a day, you can get 24-hour heartburn relief.* Prilosec OTC became the first and original OTC frequent heartburn medication in 2003.

Keep reading for answers to the most frequently asked questions about Prilosec OTC.

How Prilosec OTC Works

How does Prilosec OTC work?

Prilosec OTC blocks frequent heartburn by shutting down many of the pumps in your stomach that produce excess acid.

Does Prilosec OTC work right away?

Prilosec OTC starts to work on the very first day of treatment, but may take 1 to 4 days for full effect (although some people get complete relief within 24 hours). Taking Prilosec OTC every day for 14 days helps to ensure that acid production is consistently controlled.

How to Take Prilosec OTC

How often should I take Prilosec OTC?

Prilosec OTC is a 14-day regimen that can be used up to three times a year, but not more often than every 4 months. If you need to use Prilosec OTC for more than the three indicated 14-day courses of treatment, consult with your doctor. Here’s why: By talking with your doctor first, you and your doctor will ensure you’re not missing a bigger health
problem, such as  GERD
, and determine if Prilosec OTC continues to be right for you. Do not take Prilosec OTC for more than 14 days or more often than every 4 months unless directed by a doctor.

What if I miss a day of heartburn treatment?

If you miss a day, just continue your treatment on the next day.

What do I do after 14 days?

If your frequent heartburn continues or returns after 14 days of treatment, stop use and talk to your doctor. Your doctor will take steps to ensure Prilosec OTC is not masking any potentially serious underlying conditions behind your frequent heartburn, and determine if Prilosec OTC continues to be right for you. Do not take Prilosec OTC for more than 14 days or more often than every 4 months unless directed by a doctor.

If I am taking Prilosec OTC, can I eat the foods that used to give me frequent heartburn?

Yes. Prilosec OTC blocks heartburn before it begins so you can enjoy the foods you love, as a part of a heartburn-friendly diet.*

Can I take Prilosec OTC more than once a day?

No. As part of a course of therapy, take only one pill a day to treat frequent heartburn for 24 hours.* Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor.

Can I take Prilosec OTC if I’m pregnant?

If pregnant or breast-feeding, ask a healthcare professional before use.

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What else do I need to know about Prilosec OTC?

I heard medicines with the active ingredient ‘Ranitidine’ contain a probable carcinogen. Should I be worried about Prilosec OTC?

You can trust in Prilosec OTC as an FDA approved, safe and effective remedy to relieve frequent heartburn symptoms. Prilosec OTC (equivalent to Omeprazole 20 mg) has the longest history of safe & effective consumer use of any OTC PPI. Prilosec OTC is not in the same class of drugs referenced in the recent FDA study and does not contain the active pharmaceutical ingredient ‘Ranitidine’ mentioned in the study.

As with any OTC medication, it is important to read and follow all label directions to ensure proper dosing and to avoid drug interactions. Prilosec OTC is to be used once a day, every day for 14 days as a course of treatment. Do not take for more than 14 days or more oftent han every 4 months unless directed by a doctor.

Does Prilosec OTC interact negatively with other drugs?

It's possible. Ask a doctor or pharmacist before use if you are taking a prescription drug. Acid reducers may interact with certain prescription drugs.

Prescription Prilosec vs. Prilosec OTC

What does “OTC” stand for?

“OTC” stands for “over-the-counter.” Prilosec OTC became available over the counter in 2003.

Is prescription Prilosec® the same as Prilosec OTC?

Prilosec and Prilosec OTC are different in indication and dose form. Prilosec OTC is indicated for the treatment of frequent heartburn (heartburn that occurs two or more days per week). Prilosec is a prescription medication indicated for the treatment of many other acid-related conditions. However, the omeprazole active ingredient in Prilosec became available over-the-counter in 2003 in the form of Prilosec OTC. Omeprazole magnesium, the active ingredient in Prilosec OTC, is equivalent to the active ingredient in Prilosec to treat frequent heartburn. Please follow the dosing instructions on the package or as directed by your physician.

Is Prilosec OTC strong enough to help me?

Prilosec OTC is in the strongest class of frequent heartburn medicines available over-the-counter. It blocks frequent heartburn before it begins with one pill a day for 14 days.*

What happens if I take Prilosec OTC after I started to feel heartburn coming on?

If you are a frequent heartburn sufferer, you don't have to wait until you have heartburn symptoms to take Prilosec OTC. It begins working on the very first day of treatment, and with one pill each morning for 14 days you can get zero heartburn.*

If Prilosec OTC is available over-the-counter, why do I need to talk to my doctor?

As with any OTC drug, it is important to read and follow all label directions. If you have questions regarding the label or use of Prilosec OTC, talk with your doctor or pharmacist.

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