Person clutching chest with both hands red glow indicating pain or discomfort in the chest area.

Heartburn and Acid Reflux: Are They the Same Thing?

*Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Use as directed.

Sources:

  1. National Library of Medicine. Heartburn: what you need to know. MedlinePlus Magazine. January 20, 2020. Accessed April 28, 2025.
    https://magazine.medlineplus.gov/article/heartburn-what-you-need-to-know
  2. National Library of Medicine. Gastroesophageal reflux disease. MedlinePlus Magazine. Last reviewed January 30th, 2023. Accessed June 4th, 2025.
    https://medlineplus.gov/ency/article/000265.htm#:~:text=Gastroesophageal%20reflux%20disease%20(GERD)%20is,cause%20heartburn%20and%20other%20symptoms
  3. Loma Linda University Health. Gastroesophageal Reflux Disease (GERD). Loma Linda University Health website. Accessed June 4, 2025.
    https://lluh.org/conditions/gastroesophageal-reflux-disease-gerd
  4. Johns Hopkins Medicine. GERD Diet: Foods That Help With Acid Reflux Heartburn. Johns Hopkins Medicine. Accessed
    https://www.hopkinsmedicine.org/health/wellness-and-prevention/gerd-diet-foods-that-help-with-acid-reflux-heartburn


^ IQVIA ProVoice Survey, 2005-2025.

†Pharmacy Times 2025-2026 Survey of Pharmacists’ OTC Recommendations

* Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Use as directed.

** PG Calculation based in part on Buying Households reported by the Nielsen Company through its Homescan Panel service in the US for Prilosec OTC for the period of 8/31/03 through 6/25/16